| Institution | Chapter | Year |
| Harvard University | Alpha of Massachusetts* | 1779 |
| Amherst College | Beta of Massachusetts | 1853 |
| Williams College | Gamma of Massachusetts | 1864 |
| Tufts University | Delta of Massachusetts | 1892 |
| Boston University | Epsilon of Massachusetts | 1899 |
| Smith College | Zeta of Massachusetts | 1904 |
| Wellesley College | Eta of Massachusetts | 1904 |
| Mount Holyoke College | Theta of Massachusetts | 1905 |
| Radcliffe College | Iota of Massachusetts* | 1914 |
| Wheaton College | Kappa of Massachusetts | 1932 |
| Clark University | Lambda of Massachusetts | 1953 |
| Brandeis University | Mu of Massachusetts | 1962 |
| University of Massachusetts | Nu of Massachusetts | 1965 |
| Massachusetts Institute of Technology | Xi of Massachusetts | 1971 |
| Boston College | Omicron of Massachusetts | 1971 |
| College of the Holy Cross | Pi of Massachusetts | 1974 |
*The Alpha chapter at Harvard University and the Iota chapter at Radcliffe College voted to merge as the Alpha-Iota chapter of Massachusetts at Harvard University, effective June 1995.